15-15 rule


The 15-15 rule is the worldwide recommended immediate measure for mild to moderate hypoglycemia. It says: take 15 grams of quickly available carbohydrates, wait 15 minutes, measure blood sugar and repeat if necessary. In this way, blood sugar is raised safely and in a controlled manner without overshooting too much.

This is how the 15-15 rule is applied

  1. 15-20g fast carbohydrates consume immediately (e.g. dextrose, glucose gel or juice).
  2. Wait 15 minuteswithout taking in any more carbohydrates.
  3. Measure blood sugar.
  4. If the values are still below 70 mg/dl, repeat the rule.
  5. Once blood sugar is above 70 mg/dL, eat a meal or snack containing slow carbohydrates to keep the level stable.

Practical quantities for 15 g of dextrose

product Amount for approx. 15 g of dextrose
Coated mini-tablets (200 mg) 75 tablets
Dextrose powder 15 g (approx. 3 level teaspoons)
Classic glucose tablets 3-4 tablets
Glucose gel 1 tube (usually 15-20 g)

When the rule does not apply or only applies to a limited extent

  • In case of severe hypoglycemia with impaired consciousness (then glucagon or emergency doctor)
  • If ketoacidosis is suspected
  • For very low values (< 50 mg/dl) – 20–30 g is often recommended here

Tips for everyday life

  • Always have fast-acting carbohydrates at hand (e.g. Hyporest Pockets)
  • After the acute phase, plan a meal with complex carbohydrates
  • If necessary, increase the amount slightly when exercising or at night

Further information:
Diabetes mellitus – knowledge and overview
Why hyporest
Hypoglycemia

Sources

  1. German Diabetes Society (DDG). S3 guideline “Hypoglycemia”. As of 2025. Available at: www.deutsche-diabetes-gesellschaft.de/leitlinien.
  2. American Diabetes Association. Standards of Medical Care in Diabetes—2026. Diabetes Care. 2026;49(Suppl 1). Available at: diabetesjournals.org.
  3. Robert Koch Institute (RKI). Federal health reporting – diabetes mellitus in Germany. Berlin 2024.
  4. International Diabetes Federation (IDF). IDF Diabetes Atlas. 11th edition. Brussels 2025. Available at: diabetesatlas.org.

Important note:
The information in this encyclopedia article is intended solely for general and non-binding information. They do not replace medical advice, diagnosis or therapy. If you have any health questions or complaints, please always consult a doctor or qualified healthcare professional. The content was created with the greatest possible care, but errors cannot be completely ruled out.

Last updated: February 26, 2026